Scientist I, Cell Therapy Editing Strategy and Analytics

Astellas is a global life sciences company developing innovative therapies and healthcare solutions for diseases with high unmet medical need. The Scientist I will provide bench-based scientific expertise to enhance gene-editing capabilities for cell therapy, develop editing strategies and processes, analyze edited cells, and support cross-functional process development activities and program timelines.

What you'll do:

• Design and execute complex and novel gene-editing of pluripotent stem cells to develop strategies compatible with controlled cell therapy manufacturing applications and generate representative clones for downstream teams
• Lead efforts to evaluate and improve new cutting-edge gene editing technologies, develop genome engineering designs and molecular and cellular assays for characterization of edited cells
• Perform data collection, analysis, troubleshooting and interpretation with a high degree of scientific rigor
• Demonstrates understanding of process development, proactively identifies challenges and proposes solutions to management in a timely manner
• Work cross-functionally, including project teams, to contribute to internal milestone achievements and generation of key deliverables
• Communicate results in both oral and written formats by participating regularly in team meeting preparations and presentations, including cross-functional team meetings
• Support preparation and review of technical slide decks, reports, Standard Operating Procedures (SOPs)regulatory filings and tech transfer
• Ensure smooth day-to-day operations, including on the weekends
• Perform other duties as assigned or special projects as needed
• Stay up to date on literature and mentor junior members